Detalhe da pesquisa
1.
Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell
; 178(3): 567-584.e19, 2019 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31348886
2.
Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
Cell
; 165(2): 449-63, 2016 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26949186
3.
Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity
; 50(3): 677-691.e13, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30876875
4.
A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat Chem Biol
; 19(3): 284-291, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36411391
5.
Antiviral Activity and Crystal Structures of HIV-1 gp120 Antagonists.
Int J Mol Sci
; 23(24)2022 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36555641
6.
Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design.
J Virol
; 90(13): 5899-5914, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27053554
7.
Phase 1 trial evaluating safety and pharmacokinetics of HIV-1 broadly neutralizing mAbs 10E8VLS and VRC07-523LS.
JCI Insight
; 9(7)2024 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38587079
8.
Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain.
MAbs
; 15(1): 2223350, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37345226
9.
Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat Struct Mol Biol
; 30(9): 1323-1336, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37605043
10.
Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency.
MAbs
; 15(1): 2165390, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36729903
11.
Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Structure
; 30(6): 862-875.e4, 2022 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35413243
12.
A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention.
MAbs
; 13(1): 1946918, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34328065
13.
Prognostic significance of Notch 3 gene expression in ovarian serous carcinoma.
Cancer Sci
; 101(9): 1977-83, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20624166
14.
HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies.
Cell Rep
; 31(4): 107583, 2020 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32348769
15.
Safety and pharmacokinetics of broadly neutralising human monoclonal antibody VRC07-523LS in healthy adults: a phase 1 dose-escalation clinical trial.
Lancet HIV
; 6(10): e667-e679, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31473167
16.
Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody.
Cell Rep
; 22(7): 1798-1809, 2018 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29444432
17.
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat Med
; 24(6): 857-867, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29867235
18.
The use of green fluorescence gene (GFP)-modified rabbit mesenchymal stem cells (rMSCs) co-cultured with chondrocytes in hydrogel constructs to reveal the chondrogenesis of MSCs.
Biomaterials
; 30(31): 6374-85, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19682739